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Likewise, in FLAD1-related mitochondrial diseases, although the enzyme that synthesizes FAD is impaired, high-dose riboflavin may saturate the residual activity and promote correct folding, bypassing the synthesis bottleneck

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The most common adverse events are gut (nausea, vomiting, diarrhea), very during dose escalation

[DOI] [PubMed] [Google Scholar] 16.Jakicic JM, Davis KK, Rogers RJ, Feasibility of integration of yoga in a behavioral weight-loss intervention: a randomized trial